Permanent hair removal of white, grey and light blond hair after laser treatment combined with melanin encapsulated liposomes. (Lipoxôme®)

Until now, people suffering from unwanted, non-pigmented hair grow (white, grey and light blond) could not effectively been treated by photothermolysis. Melanin encapsulated liposomes are able to target melanin into the hair follicle. Melanin is the primary chromophore for laser hair removal. The external application of these liposomes prior to laser treatment ables to achieve permanent hair removal. Objective: Monitoring the efficacy of lasers and intense pulsed light sources when used for the permanent hair removal with the use of melanin encapsulated liposomes (Lipoxôme®). 40 patients suffering from unwanted, non-pigmented hair grow (white, grey and light blond) were treated with a diode laser once every 6-8-weeks after external application of melanin encapsulated liposomes. Results: 40 patients with white, grey and light blond hair in the face (hirsutism) have been treated with a Diode Laser. Melanin encapsulated liposomes (Lipoxôme®) were applied to the treatment area, 6 to 8 times a day, during the 14 days prior to the laser treatment. Six months after the last lasertreatment, most patients (90.0%) had considerable hair reduction (75100 %). 62,5 % of the patients achieved a permanent hair reduction between 95 100%. Photographs were taken before, during and at the end of treatment(fig.a,b) Introduction Unwanted facial and body hair can represent a severe cosmetic disturbance with social and psychological implications often strong enough to motivate patients, especially women, to seek dermatological treatment. The phenomenon of unwanted hair can be divided into three main categories: Hypertrichosis is excessive hair in a normal distribution or in abnormal locations. The cause of universal hypertrichosis is most commonly genetic and often seen in Caucasian women from the Mediterranean and Middle East. Hypertrichosis can also occur as a secondary effect of endocrine and metabolic disturbances, from medication side effects, tumors, neurological diseases, anorexia nervosa and various dermatological entities as Becker's nevi and congenital nevi. Hirsutism describes hair growth in women in a male pattern distribution. This occurs as idiopathic hirsutism